In the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial, compared with placebo, the patients with a recent stroke or transient ischemic attack (TIA) randomized to atorvastatin 80 mg/day had a significant 16% relative risk reduction of stroke, and a 35% reduction in major coronary events.
Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk. Statins are a family of medications that lower cholesterol.
Even more amoxicillin leukopenia, they lower the chances of having a heart attack or stroke. Statins have pleiotropic effects of potential neuroprotection. However, because of lack of large randomized clinical trials, current guidelines do.
Submit Manuscript, Journal of Neurology & Stroke. The Current Status of Statins in Stroke Prevention. Editorial. High-Dose Statins Should Be Used in All Acute Ischemic Strokes. Majaz Moonis. Download PDF.
Stroke. Statins before and after an ischemic stroke may improve functional outcomes and survival, but the association is not exactly straightforward. 4. Overview of Clinical Trials.
5. Primary Stroke Prevention and Statins. 6. Meta-Analysis. 7. Is Statins' Benefit Mediated Only Through Cholesterol Reduction? 8.